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Climate change research roundup: hiding heat in the Atlantic and the Arctic carbon cycle
The most recent issue of Science has two new reports on the so-called global warming hiatus and the carbon cycle in the Arctic, both of which are central to discussions of climate change and where temperature increases are being seen around … Continue reading →

Cory, R., Ward, C., Crump, B. & Kling, G. (2014). Sunlight controls water column processing of carbon in arctic fresh waters, Science, 345 (6199) 925-928. DOI: 10.1126/science.1253119

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The Learning Brain Unravelled
As an engineer you would think math would come easy to me, it didn’t. Funny thing though, science in general and biology in particular came very easy to me. The […]

Patrick T. Sadtler,, Kristin M. Quick,, Matthew D. Golub,, Steven M. Chase,, Stephen I. Ryu,, Elizabeth C. Tyler-Kabara,, Byron M. Yu, & Aaron P. Batista (2014). Neural constraints on learning, Nature, Other:

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Video Tip of the Week: Phenoscape, captures phenotype data across taxa
Development of the skeleton is a good example of a process that is highly regulated, requires a lot of precision, is conserved and important relationships across species, and is fairly easy to detect when it’s gone awry. I mean–it’s hard to know at a glance if all the neurons in an organism got to the […]

Mabee B.P., Balhoff J.P., Dahdul W.M., Lapp H., Midford P.E., Vision T.J. & Westerfield M. (2012). 500,000 fish phenotypes: The new informatics landscape for evolutionary and developmental biology of the vertebrate skeleton., Zeitschrift fur angewandte Ichthyologie = Journal of applied ichthyology, PMID: http://www.ncbi.nlm.nih.gov/pubmed/22736877

Balhoff J.P., Cartik R. Kothari, Hilmar Lapp, John G. Lundberg, Paula Mabee, Peter E. Midford, Monte Westerfield & Todd J. Vision (2010). Phenex: Ontological Annotation of Phenotypic Diversity, PLoS ONE, 5 (5) e10500. DOI: http://dx.doi.org/10.1371/journal.pone.0010500

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Co-Chaperone Keeps Close Watch on Mice Sperm Production
Chaperones aren't just for high-school homecoming dances. Cells have chaperones as well, chaperone proteins that ensure newly made proteins are properly folded. If protein folding goes awry, diseases associated with misfolded proteins such as Alzheimer's and Parkinson's can arise. But if one set of chaperones can throw a wet blanket on a school dance, imagine a second set of co-chaperones just to keep the chaperones in check. That's the growing picture in cellular chaperoning as folding […]

Rogon, C., Ulbricht, A., Hesse, M., Alberti, S., Vijayaraj, P., Best, D., Adams, I., Magin, T., Fleischmann, B. & Hohfeld, J. & (2014). HSP70-binding protein HSPBP1 regulates chaperone expression at a posttranslational level and is essential for spermatogenesis, Molecular Biology of the Cell, 25 (15) 2260-2271. DOI: 10.1091/mbc.E14-02-0742

Alberti S, Böhse K, Arndt V, Schmitz A, Höhfeld J. (2004). The Cochaperone HspBP1 Inhibits the CHIP Ubiquitin Ligase and Stimulates the Maturation of the Cystic Fibrosis Transmembrane Conductance Regulator, Molecular Biology of the Cell, 15 (9) 4003-4010. DOI: 10.1091/mbc.E04-04-0293

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Prenatal SSRI exposure and autistic traits
A quote to start today's post: "Our results suggest an association between prenatal SSRI exposure and autistic traits in children". That was a primary finding reported by Hanan El Marroun and colleagues [1] who looked at whether maternal depressive symptoms or a class of quite commonly used pharmaceutics - the selective serotonin reuptake inhibitors (SSRIs) - used to manage depressive symptoms, during pregnancy might impact on offspring development."Everything the light touches is our […]

Marroun, H., White, T., van der Knaap, N., Homberg, J., Fernandez, G., Schoemaker, N., Jaddoe, V., Hofman, A., Verhulst, F., Hudziak, J. & Stricker, B. (2014). Prenatal exposure to selective serotonin reuptake inhibitors and social responsiveness symptoms of autism: population-based study of young children, The British Journal of Psychiatry, 205 (2) 95-102. DOI: 10.1192/bjp.bp.113.127746

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The Holographic Universe [we might Live in!]
Are you feeling a little… flat? Well that might be because you are only in 2 dimensions. I know what you’re thinking, insane! Well first check the name of the […]

Cowen, R. (2013). Simulations back up theory that Universe is a hologram, Nature, DOI: 10.1038/nature.2013.14328

Li W & Takayanagi T (2011). Holography and entanglement in flat spacetime., Physical review letters, 106 (14) 141301. PMID: http://www.ncbi.nlm.nih.gov/pubmed/21561179

Piao, Y. (2007). Primordial perturbation spectra in a holographic phase of the Universe, Physical Review D, 76 (4) DOI: 10.1103/PhysRevD.76.043509

George F. Smoot (2010). Go with the Flow, Average Holographic Universe, Int.J.Mod.Phys.D19:2247-2258,2010, arXiv: http://arxiv.org/abs/1003.5952v1

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For These Bats, the Best Falsetto Wins Over the Ladies
A bat’s voice is its livelihood. Chirping and squeaking at just the right frequencies lets it echolocate food and stay alive. Sounding pretty isn’t the point—except when it is. For the first time, scientists think they’ve found a bat species in which females choose mates based on their voices. Even if a lower-frequency squeak might […]The post For These Bats, the Best Falsetto Wins Over the Ladies appeared first on Inkfish.

Puechmaille, S., Borissov, I., Zsebok, S., Allegrini, B., Hizem, M., Kuenzel, S., Schuchmann, M., Teeling, E. & Siemers, B. (2014). Female Mate Choice Can Drive the Evolution of High Frequency Echolocation in Bats: A Case Study with Rhinolophus mehelyi, PLoS ONE, 9 (7) DOI: 10.1371/journal.pone.0103452

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76% of youths with autism meet ADHD diagnostic criteria?
Autism is not normally a stand-alone diagnosis. I've mentioned that point a few times on this blog, stressing how a clinical diagnosis of autism appears to increase the risk of various other behavioural, psychiatric and somatic diagnoses also [variably] being present over a lifetime. Part of that comorbidity has been talked about in discussions about ESSENCE (see here) and the excellent document produced by Treating Autism on medical comorbidities occurring alongside autism (see here) for […]

Joshi G, Faraone SV, Wozniak J, Tarko L, Fried R, Galdo M, Furtak SL & Biederman J (2014). Symptom Profile of ADHD in Youth With High-Functioning Autism Spectrum Disorder: A Comparative Study in Psychiatrically Referred Populations., Journal of attention disorders, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25085653

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Zombie Ant Fungi knows it’s prey
So awhile back I was bored and to kill some time wisely I wrote this little bit on real life (sometime potential) zombies. It featured a special section on a […]

de Bekker C, Quevillon LE, Smith PB, Fleming KR, Ghosh D, Patterson AD & Hughes DP (2014). Species-specific ant brain manipulation by a specialized fungal parasite., BMC evolutionary biology, 14 (1) 166. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25085339

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Unpacking Recovery Part 3: Can Patients Imagine Recovery?
Today I have the distinct pleasure of writing about one of my favourite articles about eating disorder recovery by Malson et al. (2011) exploring how inpatients talk about eating disorder recovery. I have personally found this article to be very helpful in understanding some of the difficulties of understanding and achieving recovery in our social context. As Malson and colleagues explain (and as we’ve established), eating disorder recovery is elusive. Often, poor prognosis is described […]

Malson H, Bailey L, Clarke S, Treasure J, Anderson G & Kohn M (2011). Un/imaginable future selves: a discourse analysis of in-patients' talk about recovery from an 'eating disorder'., European eating disorders review : the journal of the Eating Disorders Association, 19 (1) 25-36. PMID: http://www.ncbi.nlm.nih.gov/pubmed/21182163

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