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When Crazy becomes a Crime
My friend has a glass eye, you would never notice and unless you knew the story you might not think anything of it. His older brother did it. Yes, you […]

Dana Goldman,, John Fastenau,, Riad Dirani,, Eric Hellend,, Geoff Joyce,, Ryan Conrad, & Darius Lakdawalla, (2014). Medicaid Prior Authorization Policies and Imprisonment Among Patients With Schizophrenia, The American Journal of Managed Care, 20 (7) Other:

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Fasting Improves Recovery of Bone Marrow Stem Cells after Chemotherapy
[Note: This is a guest post by Tauseef (@CellSpell)] Fasting is defined as either completely abstaining from or minimizing food intake for a defined period time - ranging from about 12 hours to even a few weeks. Calorie restriction, on the other hand, refers to an overall reduction in the daily calorie intake by about 20%-40% without necessarily reducing the meal intake frequency. Although calorie restriction is well-suited for weight loss and thus also reduces the risk of chronic diseases... […]

Cheng, C., Adams, G., Perin, L., Wei, M., Zhou, X., Lam, B., Da Sacco, S., Mirisola, M., Quinn, D., Dorff, T. & Kopchick, J. (2014). Prolonged Fasting Reduces IGF-1/PKA to Promote Hematopoietic-Stem-Cell-Based Regeneration and Reverse Immunosuppression, Cell Stem Cell, 14 (6) 810-823. DOI: 10.1016/j.stem.2014.04.014

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Fasting Improves Recovery of Bone Marrow Stem Cells after Chemotherapy
[Note: This is a guest post by Tauseef (@CellSpell)] Fasting is defined as either completely abstaining from or minimizing food intake for a defined period time - ranging from about 12 hours to even a few weeks. Calorie restriction, on the other hand, refers to an overall reduction in the daily calorie intake by about 20%-40% without necessarily reducing the meal intake frequency. Although calorie restriction is well-suited for weight loss and thus also reduces the risk of chronic diseases... […]

Cheng, C., Adams, G., Perin, L., Wei, M., Zhou, X., Lam, B., Da Sacco, S., Mirisola, M., Quinn, D., Dorff, T. & Kopchick, J. (2014). Prolonged Fasting Reduces IGF-1/PKA to Promote Hematopoietic-Stem-Cell-Based Regeneration and Reverse Immunosuppression, Cell Stem Cell, 14 (6) 810-823. DOI: 10.1016/j.stem.2014.04.014

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Optical Cables, from Thin Air!
It’s a project that would make Tesla proud. Just imagine being able to instantaneously run an optical cable or fiber to any point on earth, or even into space. That’s […]

Rosenthal, E., Jhajj, N., Wahlstrand, J. & Milchberg, H. (2014). Collection of remote optical signals by air waveguides, Optica, 1 (1) 5. DOI: 10.1364/OPTICA.1.000005

Jhajj, N., Rosenthal, E., Birnbaum, R., Wahlstrand, J. & Milchberg, H. (2014). Demonstration of Long-Lived High-Power Optical Waveguides in Air, Physical Review X, 4 (1) DOI: 10.1103/PhysRevX.4.011027

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Common variation and the genetics of autism
The paper by Trent Gaugler and colleagues [1] reporting that the genetic architecture of the autism spectrum disorders (ASDs) seems in the most part to be due to "common variation" over and above "rare variants or spontaneous glitches" adds to the quite voluminous literature in this area.Everything in proportion? @ Wikipedia Based on an analysis of "a unique epidemiological sample from Sweden" researchers looked at DNA variations in some 3000 individuals with autism and asymptomatic […]

Gaugler T, Klei L, Sanders SJ, Bodea CA, Goldberg AP, Lee AB, Mahajan M, Manaa D, Pawitan Y, Reichert J & Ripke S (2014). Most genetic risk for autism resides with common variation., Nature genetics, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25038753

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Autism and Parents: Reducing stress
Raising an autistic child can be a gift. Unfortunately it can also be challenging and stressful. Let’s be real, it’s stressful just being a parent, throw in a disability that […]

Dykens E.M. & Fisher M.H. (2014). Reducing Distress in Mothers of Children With Autism and Other Disabilities: A Randomized Trial, Pediatrics , DOI: doi: 10.1542/peds.2013-3164

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A History of Bioinformatics (told from the Year 2039)
A week or so back I was watching the chatter around the #ISMB / #BOSC2014 meeting, and saw a number of amusing and intriguing comments about Titus Brown’s keynote talk. CTB talking as if date were 2039. "'bioinformatics' and 'systems biology' are now simply 'biology" #BOSC2014 — Stephen Turner (@genetics_blog) July 11, 2014 #BOSC2014 @ctitusbrown […]

Stein L.D. (2008). Bioinformatics: alive and kicking, Genome Biology, 9 (12) 114. DOI: http://dx.doi.org/10.1186/gb-2008-9-12-114

Heinlein R. (1952). Where to?, Galaxy Magazine, February 13-22. Other:

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It's time for Western psychology to recognise that many individuals, and even entire cultures, fear happiness
It's become a mantra of the modern Western world that the ultimate aim of life is to achieve happiness. Self-help blog posts on how to be happy are almost guaranteed popularity (the Digest has its own!). Pro-happiness organisations have appeared, such as Action for Happiness, which aims to "create a happier society for everyone." Topping it all, an increasing number of governments, including in the UK, have started measuring national well-being (seen as a proxy for "happiness") - the argument […]

Joshanloo, M. & Weijers, D. (2013). Aversion to Happiness Across Cultures: A Review of Where and Why People are Averse to Happiness, Journal of Happiness Studies, 15 (3) 717-735. DOI: 10.1007/s10902-013-9489-9

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Autism and asthma yet again
"Asthma is approximately 35 % more common in autistic children".Pipe down @ Wikipedia That was the finding reported by Stanley Kotey and colleagues [1] based on their analysis of the 2007 National Survey of Children's Health (NSCH) dataset, a resource looking at "the physical and emotional health of children ages 0-17 years of age" resident in the United States. I don't intend to dwell too much on the Kotey findings aside from pointing out: (a) the reported prevalence of autism […]

Kotey, S., Ertel, K. & Whitcomb, B. (2014). Co-occurrence of Autism and Asthma in a Nationally-Representative Sample of Children in the United States, Journal of Autism and Developmental Disorders, DOI: 10.1007/s10803-014-2174-y

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Babylonian Neurology and Psychiatry
A fascinating little paper in Brain examines Neurology and psychiatry in Babylon. It’s a collaboration by British neurologist Edward H. Reynolds and Assyriologist James V. Kinnier Wilson. The sources they discuss are almost 4,000 years old, dating to the Old Babylonian Dynasty of 1894 – 1595 BC. Writing in cuneiform script impressed into clay tablets, […]The post Babylonian Neurology and Psychiatry appeared first on Neuroskeptic.

Reynolds EH & Kinnier Wilson JV (2014). Neurology and psychiatry in Babylon., Brain : a journal of neurology, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25037816

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